A heterocyclic polyketide
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Product Categories

Product Type

Biochemicals
Antibiotics
Natural Products
Microbial Metabolites

Research Area

Kibdelone A

Item No. 21524

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(10S,12S,13R)-4-chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone
CAS Number
934464-77-4
Molecular Formula
C29H24ClNO10
Formula Weight
582.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O=C1N(C)C(CCC)=C(Cl)C2=C1C(C3=C4C(C(OC)=C(C(C5=O)=C4O)OC6=C5[C@@H](O)[C@@H](O)C[C@@H]6O)=CC=C3C2=O)=O
InChi Code
InChI=1S/C29H24ClNO10/c1-4-5-11-20(30)16-17(29(39)31(11)2)23(36)14-9(21(16)34)6-7-10-15(14)24(37)19-25(38)18-22(35)12(32)8-13(33)27(18)41-28(19)26(10)40-3/h6-7,12-13,22,32-33,35,37H,4-5,8H2,1-3H3/t12-,13-,22-/m0/s1
InChi Key
VXXQRIDYOXHDCN-MZFXBISCSA-N
Origin
Bacterium/Kibdelosporangium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $314

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    Product Description

    Kibdelone A is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete, Kibdelosporangium.1 Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines.1 They also display significant antibacterial and nematocidal activity.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ratnayake, R., Lacey, E., Tennant, S., et al. Kibdelones: Novel anticancer polyketides from a rare Australian actinomycete. Chemistry 13(5), 1610-1619 (2007).