An Analytical Reference Standard
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Synonyms
Synonyms
  • (S)-Zopiclone
Technical Information
Formal Name
4-methyl-1-piperazinecarboxylic acid, (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
CAS Number
138729-47-2
Molecular Formula
C17H17ClN6O3
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 10 mg/mlDMF:PBS (pH 7.2)(1:3): 0.25 mg/mlDMSO: 2 mg/ml
SMILES
O=C1N(C2=CC=C(Cl)C=N2)[C@@H](OC(N3CCN(C)CC3)=O)C4=NC=CN=C41
InChi Code
InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChi Key
GBBSUAFBMRNDJC-INIZCTEOSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Eszopiclone (Item No. 21530) is an analytical reference standard categorized as a sedative and hypnotic.1 Eszopiclone reduces wakefulness and the latency to sleep onset, as well as increases the time spent in non-rapid eye movement (NREM) sleep, in mice and sleep-deprived mice.2 Eszopiclone is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nutt, D.J., and Stahl, S.M. Searching for perfect sleep: The continuing evolution of GABAA receptor modulators as hypnotics. J. Psychopharmacol. 24(11), 1601-1612 (2010).

    2. Gerashchenko, D., Pasumarthi, R.K., and Kilduff, T.S. Plasticity-related gene expression during eszopiclone-induced sleep. Sleep 40(7), zsx098 (2017).