A β-lactam antibiotic
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Labeled Version(s)
36772Penicillin G-d5 (potassium salt)
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Penicillin G (potassium salt)

Item No. 21615

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monopotassium salt
CAS Number
113-98-4
Synonyms
  • Benzylpenicillin
  • NSC 131815
Molecular Formula
C16H17N2O4S • K
Formula Weight
372.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
O=C(N[C@@H]1C(N2[C@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O)CC3=CC=CC=C3.[K+]
InChi Code
InChI=1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
InChi Key
IYNDLOXRXUOGIU-LQDWTQKMSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Penicillin G is a β-lactam antibiotic that is effective mainly for Gram-positive bacteria.1 It has MIC90 values of 0.03, 1, and 4 µg/ml for penicillin-susceptible, -intermediate, and -resistant strains of S. pneumoniae, respectively, and 16-128 µg/ml for various Bacteroides isolates in a broth dilution assay.2,3 Formulations containing penicillin G have been used for the treatment of bacterial infections and in livestock production.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Demain, A.L. Production of beta-lactam antibiotics and its regulation. Proc. Natl. Sci. Counc. Repub. China B. 15(4), 251-265 (1991).

    2. Pankuch, G.A., Lichtenberger, C., Jacobs, M.R., et al. Antipneumococcal activities of RP 59500 (quinupristin-dalfopristin), penicillin G, erythromycin, and sparfloxacin determined by MIC and rapid time-kill methodologies. Antimicrob. Agents Chemother. 40(7), 1653-1656 (1996).

    3. Aldridge, K.E., Sanders, C.V., Janney, A., et al. Comparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species. Antimicrob. Agents Chemother. 26(3), 410-413 (1984).