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Unlabeled Version(s)
21642Mazindol
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Mazindol-d4

Item No. 21640

Restricted Product (Schedule IV)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol-d4
CAS Number
1246815-50-8
Molecular Formula
C16H9ClD4N2O
Formula Weight
288.8
Purity
≥99% deuterated forms (d1-d4)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: Slightly solubleEthanol: Slightly soluble
λmax
225, 268 nm
SMILES
OC1(C2=CC=C(Cl)C=C2)N3C(C4=CC=CC=C41)=NC([2H])([2H])C3([2H])[2H]
InChi Code
InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2/i9D2,10D2
InChi Key
ZPXSCAKFGYXMGA-YQUBHJMPSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Mazindol-d4 (Item No. 21640) is intended for use as an internal standard for the quantification of mazindol (Item No. 21642) by GC- or LC-MS. Mazindol is categorized as a stimulant and inhibitor of norepinephrine, dopamine, and serotonin reuptake.1 It decreases high-fat diet-induced weight gain in mice without eliciting abuse potential or increasing locomotor activity.2 Formulations containing mazindol have previously been used in the management of obesity. Mazindol-d4 is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Konofal, E., Arnulf, I., Bizot, J.C., et al. Mazindol immediate-release/sustained-release (IR/SR): A 50-Year legacy of multifaceted mechanisms and emerging therapeutic potential. Clin. Drug Investig. 46(3), 259-280 (2026).

    2. Aotani, D., Son, C., Shimizu, Y., et al. Reevaluation of anti-obesity action of mazindol and elucidation of its effect on the reward system. Neurosci. Lett. 633, 141-145 (2016).