An antiparasitic and antimicrobial nitroimidazole
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Tinidazole

Item No. 21755

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
CAS Number
19387-91-8
Synonyms
  • CP 12,574
Molecular Formula
C8H13N3O4S
Formula Weight
247.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS (pH 7.2) (1:8): 0.11 mg/mlDMSO: 10 mg/mlEthanol: 0.2 mg/ml
λmax
230, 310 nm
SMILES
CC1=NC=C([N+]([O-])=O)N1CCS(CC)(=O)=O
InChi Code
InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
InChi Key
HJLSLZFTEKNLFI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 g

    $38

    Add

    50 g

    $84

    Add

    100 g

    $129

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Tinidazole is a 5-nitroimidazole derivative with antiparasitic and antibiotic activity that exhibits a mean minimum inhibitory concentration of 0.31, 2.33, and 0.5 μg/mL against C. difficile, P. bivia, and B. fragilis, respectively.1,2 It is orally bioavailable and is rapidly metabolized to cytotoxic intermediates that covalently bind DNA, causing irreversible damage to susceptible cells.1,2 It shows efficacy against pathogenic protozoa (T. vaginalis, E. bistolytica, and G. duodenalis), clinically significant anaerobic bacteria (B. fragilis, C. difficile), and microaerophilic bacterium (H. pylori).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Citron, D.M., Tyrrell, K.L., Warren, Y.A., et al. In vitro activities of tinidazole and metronidazole against Clostridium difficile, Prevotella bivia and Bacteroides fragilis. Anaerobe 11(6), 315-317 (2005).

    2. Fung, H.B., and Doan, T.L. Tinidazole: A nitroimidazole antiprotozoal agent. Clin. Ther. 27(12), 1859-1884 (2005).