A fungal metabolite with activity against M. tuberculosis
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Viridicatin

Item No. 21763

Technical Information
Formal Name
3-hydroxy-4-phenyl-2(1H)-quinolinone
CAS Number
129-24-8
Synonyms
  • NSC 656625
Molecular Formula
C15H11NO2
Formula Weight
Purity
≥99%
A solid
DMF: solubleDMSO: solubleEthanol: moderately solubleMethanol: moderately soluble
SMILES
[H]N(C1=CC=CC=C1C(C2=CC=CC=C2)=C3O)C3=O
InChi Code
InChI=1S/C15H11NO2/c17-14-13(10-6-2-1-3-7-10)11-8-4-5-9-12(11)16-15(14)18/h1-9,17H,(H,16,18)
InChi Key
QSRVMXWVVMILDI-UHFFFAOYSA-N
Origin
Fungus/Penicillium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Viridicatin is a fungal metabolite isolated from various Penicillium species.1,2 This agent exhibits in vitro antibiotic activity against M. tuberculosis (1:15,000 dilution) but no activity against other tested bacterial strains.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Santini, A., Mikusová, P., Sulyok, M., et alPenicillium strains isolated from Slovak grape berries taxonomy assessment by secondary metabolite profile. Mycotoxin Res. 30(4), 213-220 (2014).

    2. Cunningham, K.G., and Freeman, G.G. The isolation and some chemical properties of viridicatin, a metabolic product of Penicillium viridicatum westling. Biochem J. 53(2), 328-332 (1953).