A component of the antimycin A complex and an inhibitor of ATP-citrate lyase
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Antimycin A2

Item No. 21997

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxybenzamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate
CAS Number
27220-57-1
Molecular Formula
C27H38N2O9
Formula Weight
534.6
Purity
≥85%
Formulation
A semi-solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
CCCC(O[C@@H]([C@@H]1C)[C@H](C(O[C@@H]([C@@H](C(O1)=O)NC(C(C=CC=C2NC([H])=O)=C2O)=O)C)=O)CCCCCC)=O
InChi Code
InChI=1S/C27H38N2O9/c1-5-7-8-9-12-19-24(38-21(31)11-6-2)17(4)37-27(35)22(16(3)36-26(19)34)29-25(33)18-13-10-14-20(23(18)32)28-15-30/h10,13-17,19,22,24,32H,5-9,11-12H2,1-4H3,(H,28,30)(H,29,33)/t16-,17+,19-,22+,24+/m1/s1
InChi Key
LYDAGTPXPZARPR-GFRRLMGDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $329

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    2.5 mg

    $1,562

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    Product Description

    Antimycin A2 is a component of the antimycin A complex (Item No. 34799) and an inhibitor of ATP-citrate lyase (Ki = 4.2 µM).1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, J., Wen, Y., Chen, X., et al. Preparative separation of six antimycin A components from antimycin fermentation broth by high-speed counter-current chromatography. J. Chromatogr. A. 1217(36), 5687-5692 (2010).

    2. Barrow, C.J., Oleynek, J.J., Marinelli, V., et al. Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp. J. Antibiot. (Tokyo) 50(9), 729-733 (1997).