A component of the antimycin A complex and an inhibitor of ATP-citrate lyase
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Antimycin A4

Item No. 21999

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S,6S,7R,8R)-8-butyl-3-(3-formamido-2-hydroxybenzamido)-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl, butyrate
CAS Number
27220-59-3
Molecular Formula
C25H34N2O9
Formula Weight
506.6
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
CCCC(O[C@@H]([C@@H]1C)[C@H](C(O[C@@H]([C@@H](C(O1)=O)NC(C(C=CC=C2NC([H])=O)=C2O)=O)C)=O)CCCC)=O
InChi Code
InChI=1S/C25H34N2O9/c1-5-7-10-17-22(36-19(29)9-6-2)15(4)35-25(33)20(14(3)34-24(17)32)27-23(31)16-11-8-12-18(21(16)30)26-13-28/h8,11-15,17,20,22,30H,5-7,9-10H2,1-4H3,(H,26,28)(H,27,31)/t14-,15+,17-,20+,22+/m1/s1
InChi Key
GYANSQKXOLFAFP-IRSNHEQCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $255

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    2.5 mg

    $1,206

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    Product Description

    Antimycin A4 is a component of the antimycin A complex (Item No. 34799) and an inhibitor of ATP-citrate lyase (Ki = 64.8 µM).1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, J., Wen, Y., Chen, X., et al. Preparative separation of six antimycin A components from antimycin fermentation broth by high-speed counter-current chromatography. J. Chromatogr. A. 1217(36), 5687-5692 (2010).

    2. Barrow, C.J., Oleynek, J.J., Marinelli, V., et al. Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp. J. Antibiot. (Tokyo) 50(9), 729-733 (1997).