An internal standard for the quantification of Girard's reagent P
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Unlabeled Version(s)
601541Girard's Reagent P
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Girard’s Reagent P-d5

Item No. 22005

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(2-hydrazinyl-2-oxoethyl)-pyridinium-2,3,4,5,6-d5, monochloride
CAS Number
1505505-87-2
Synonyms
  • Girard P hydrazine-d5
  • GirP-d5
  • GP-d5
Molecular Formula
C7H5D5N3O • Cl
Formula Weight
192.7
Purity
≥99% deuterated forms (d1-d5)
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
260 nm
SMILES
[2H]C1=C([2H])C([2H])=C([2H])C([2H])=[N+]1CC(NN)=O.[Cl-]
InChi Code
InChI=1S/C7H9N3O.ClH/c8-9-7(11)6-10-4-2-1-3-5-10;/h1-5H,6,8H2;1H/i1D,2D,3D,4D,5D;
InChi Key
NDXLVXDHVHWYFR-GWVWGMRQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

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    10 mg

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    25 mg

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    50 mg

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    Product Description

    Girard's reagent P-d5 is intended for use as an internal standard for the quantification of Girard's reagent P (Item No. 601541) by GC- or LC-MS. Girard's reagent P is a cationic hydrazine reagent.1 It has been used as a derivatization reagent to quantify glycans, oxysterols, and 5-methylcytosine derivatives.2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wheeler, O.H. The Girard Reagents. Chem. Rev. 62(3), 205–221 (1962).

    2. Wang, C., Wu, Z., Yuan, J., et al. Simplified quantitative glycomics using the stable isotope label Girard’s reagent P by electrospray ionization mass spectrometry. J. Proteome Res. 13(2), 372-384 (2014).

    3. Griffiths, W.J., Abdel-Khalik, J., Crick, P.J., et al. Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients. J. Steroid Biochem. Mol. Biol. 169, 77-87 (2017).

    4. Tang, Y., Xiong, J., Jiang, H.-P., et al. Determination of oxidation products of 5-methylcytosine in plants by chemical derivatization coupled with liquid chromatography/tandem mass spectrometry analysis. Anal. Chem. 86(15), 7764-7772 (2014).