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SL-651,498

Item No. 22008

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-fluoro-2,9-dihydro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-1H-pyrido[3,4-b]indol-1-one
CAS Number
205881-86-3
Molecular Formula
C23H20FN3O2
Formula Weight
389.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: >100mM
λmax
238 nm
SMILES
O=C1N(C2=CC=CC=C2)C=C(C(N3CCCC3)=O)C4=C1N(C)C5=C4C=C(F)C=C5
InChi Code
InChI=1S/C23H20FN3O2/c1-25-19-10-9-15(24)13-17(19)20-18(22(28)26-11-5-6-12-26)14-27(23(29)21(20)25)16-7-3-2-4-8-16/h2-4,7-10,13-14H,5-6,11-12H2,1H3
InChi Key
QQWHWWDIFGNCLV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    SL-651,498 (Item No. 22008) is an analytical reference standard categorized as a nonbenzodiazepine anxiolytic.1 SL-651,498 has anxiolytic and anticonvulsant effects in rodents that are not associated with physical dependence or the development of anticonvulsant tolerance. It also does not induce sedation at anxiolytic-relevant doses in rats. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Griebel, G., Perrault, G., Simiand, J., et al. SL651498: A anxioselective compound with functional selectivity for a2- and a3-containing g-aminobutyric acidA (GABAA) receptors. J. Pharm. Exp. Ther. 298(2), 753-768 (2001).