We collect cookies for vital website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.

Please be advised that Cayman's phone system will be unavailable starting at 4PM ET for maintenance purposes. For immediate assistance please email our customer service department at custserv@caymanchem.com. Please continue placing orders via our website, via email at orders@caymanchem.com, or via fax at 734-971-3640.

Citrullinated Vimentin Monoclonal Antibody (Clone 12G11)

Item № 22054
product image
     100 µg $329.00 0.00

Pricing updated 2019-03-20. Prices are subject to change without notice.


Vimentin is a cytoskeleton intermediate filament protein present in cells of mesenchymal origin, including leukocytes, endothelial cells, and smooth muscle cells. It is subject to citrullination by peptidyl arginine deiminase 2 (PAD2; Item No. 10785) under high calcium concentrations, which can occur during macrophage apoptosis.1 Citrullinated vimentin has been shown to have a role in the production of anti-citrullinated protein antibodies (ACPAs).1,2 ACPAs against citrullinated proteins, such as vimentin, are considered to be highly specific markers for rheumatoid arthritis and other autoimmune diseases.2 Cayman's Citrullinated Vimentin Monoclonal Antibody (Clone 12G11) can be used for Western blot and ELISA applications. The antibody recognizes citrullinated vimentin at ~54 kDa from human samples.

Recommended Products

Related Products
View Related Product Categories
Technical Information
Citrullinated peptide sequence from an internal region of human vimentin
Clone Designation
100 µg of protein G-purified IgG
Storage Buffer
PBS, pH 7.2 with 50% glycerol and 0.02% sodium azide
Cross Reactivity
  • (+) Citrullinated vimentin
  • (-) Unmodified protein
Species Reactivity
  • (+) Human citrullinated vimentin
UniProt Accession №

Warning - this product is not for human or veterinary use.

Shipping & Storage
Wet ice in continental US; may vary elsewhere
≥ 1 year
Downloads & Resources
Product Downloads

Download Product Insert

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

Get Batch-Specific Data and Documents by Batch Number

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

References & Product Citations
Product Description References

1. Asaga, H., Yamada, M., and Senshu, T. Selective deimination of vimentin in calcium ionophore-induced apoptosis of mouse peritoneal macrophages Biochem. Bioph. Res. Commun. 243(3), 641-646 (1998).

2. Soós, L., Szekanecz, Z., Szabó, Z., et al. Clinical evaluation of anti-mutated citrullinated vimentin by ELISA in rheumatoid arthritis J. Rheumatol. 34(8), 1658-1663 (2007).

Technical Support
Contact Us
  • Toll Free Phone (USA and Canada Only): (888) 526-5351
  • Direct Phone: (734) 975-3888
Cayman Contract Services

We work with scientists to accelerate their research, drug discovery, and drug development needs through our expertise in the following areas:

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640