An internal standard for the quantification of L-DOPA
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Unlabeled Version(s)
13248L-DOPA
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L-DOPA-d3

Item No. 22089

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-hydroxy-L-tyrosine-2,3,6-d3
CAS Number
53587-29-4
Synonyms
  • 3,4-Dihydroxyphenylalanine-d3
  • Levodopa-d3
Molecular Formula
C9H8D3NO4
Formula Weight
200.2
Purity
≥99% deuterated forms (d1-d3)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Water: sparingly soluble
λmax
284 nm
SMILES
OC1=C([2H])C(C[C@H](N)C(O)=O)=C([2H])C([2H])=C1O
InChi Code
InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/i1D,2D,4D
InChi Key
WTDRDQBEARUVNC-KYKRLZBASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    250 mg

    $116

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    500 mg

    $208

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    1 g

    $347

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    Product Description

    L-DOPA-d3 is intended for use as an internal standard for the quantification of L-DOPA (Item No. 13248) by GC- or LC-MS. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier.1 It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used in stroke recovery and in the treatment of Parkinson's disease.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berends, H.I., Nijlant, J.M.M., Movig, K.L.L., et al. The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review. Eur. J. Phys. Rehabil. Med. 45(4), 621-630 (2009).