A GPDH inhibitor
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Adipostatin A

Item No. 22163

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-pentadecyl-1,3-benzenediol
CAS Number
3158-56-3
Synonyms
  • NSC 776
  • 5-pentadecyl Resorcinol
Molecular Formula
C21H36O2
Formula Weight
320.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
OC1=CC(O)=CC(CCCCCCCCCCCCCCC)=C1
InChi Code
InChI=1S/C21H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-16-20(22)18-21(23)17-19/h16-18,22-23H,2-15H2,1H3
InChi Key
KVVSCMOUFCNCGX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $83

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    25 mg

    $290

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    50 mg

    $495

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    100 mg

    $743

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    Cayman Chemical
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    Product Description

    Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH; IC50 = 4.1 µM).1 It prevents triglyceride accumulation in 3T3-L1 cells when applied at 5-7.5 µM.1 Adipostatin A is cytotoxic against fibroblast carcinoma KB cell lines with an IC50 value of 10.6 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tsuge, N., Mizokami, M., Imai, S., et al. Adipostatins A and B, new inhibitors of glycerol-3-phosphate dehydrogenase. J. Antibiot. (Tokyo) 45(6), 886-891 (1992).

    2. Tanaka, A., Arai, Y., Kim, S.-N., et al. Synthesis and biological evaluation of bilobol and adipostatin A. J. Asian Nat. Prod. Res. 13(4), 290-296 (2011).