A monoterpene with diverse biological activities
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Geranyl Acetate

Item No. 22184

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2E)-3,7-dimethyl-2,6-octadien-1-ol, 1-acetate
CAS Number
105-87-3
Synonyms
  • NSC 2584
Molecular Formula
C12H20O2
Formula Weight
196.3
Purity
≥97%
Formulation (Request formulation change)
A liquid
SMILES
CC(OC/C=C(C)/CC/C=C(C)/C)=O
InChi Code
InChI=1S/C12H20O2/c1-10(2)6-5-7-11(3)8-9-14-12(4)13/h6,8H,5,7,9H2,1-4H3/b11-8+
InChi Key
HIGQPQRQIQDZMP-DHZHZOJOSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $31

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    5 g

    $73

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    10 g

    $116

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    Product Description

    Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.1 It reduces compound action potential (CAP) peak amplitude in isolated frog sciatic nerves (IC50 = 0.51 mM).2 Geranyl acetate inhibits the radial growth of M. gypsum, T. vercossum, and C. tropicalis on solid media.3 It is sporicidal against B. subtilis when used at a concentration of 1% in an agar diffusion assay.4 Geranyl acetate inhibits growth of COLO 205 cells (IC50 = 30 μM) via induction of DNA damage, cell cycle arrest at the G2/M phase, and mitochondrial apoptosis.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fischedick, J.T. Identification of terpenoid chemotypes among high (–)-trans-Δ9-tetrahydrocannabinol-producing Cannabis sativa L. cultivars. Cannabis Cannabinoid Res. 2(1), 34-47 (2017).

    2. Ohtsubo, S., Fujita, T., Matsushita, A., et al. Inhibition of the compound action potentials of frog sciatic nerves by aroma oil compounds having various chemical structures. Pharmacol. Res. Perspect. 3(2), e00127 (2015).

    3. Khayyat, S.A., and Sameeh, M.Y. Bioactive epoxides and hydroperoxides derived from naturally monoterpene geranyl acetate. Saudi Pharm. J. 26(1), 14-19 (2018).

    4. Cho, W.-I., Cheigh, C.-I., Hwang, H.-J., et al. Sporicidal activities of various surfactant components against Bacillus subtilis spores. J. Food Prot. 78(6), 1221-1225 (2015).

    5. Qi, F., Yan, Q., Zheng, Z., et al. Geraniol and geranyl acetate induce potent anticancer effects in colon cancer Colo-205 cells by inducing apoptosis, DNA damage and cell cycle arrest. J. BUON. 23(2), 346-352 (2018).