A phenolic antioxidant
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Propyl Gallate

Item No. 22293

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4,5-trihydroxy-benzoic acid, propyl ester
CAS Number
121-79-9
Synonyms
  • Antioxidant PG
  • NSC 2626
  • PG
  • n-Propyl 3,4,5-trihydroxybenzoate
Molecular Formula
C10H12O5
Formula Weight
212.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS(pH7.2) (1:2): 0.33 mg/mlDMSO: 15 mg/mlEthanol: 10 mg/ml
λmax
273 nm
SMILES
OC1=C(O)C(O)=CC(C(OCCC)=O)=C1
InChi Code
InChI=1S/C10H12O5/c1-2-3-15-10(14)6-4-7(11)9(13)8(12)5-6/h4-5,11-13H,2-3H2,1H3
InChi Key
ZTHYODDOHIVTJV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 g

    $36

    Add

    100 g

    $55

    Add

    250 g

    $128

    Add

    500 g

    $135

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Propyl gallate is an antioxidant with antimicrobial activity. It is hepatoprotective in vitro and in vivo, preventing CCl4 induced lipoperoxidation and reduction in polysomes in rat liver.1,2 Propyl gallate (100 mg/kg, i.p.) increases expression of HIF-1α, EPO, and VEGF mRNA levels and the number of normal neurons in rat brains after 8 minutes of forebrain ischemia.3 Propyl gallate in combination with potassium sorbate is bactericidal and bacteriostatic against S. aureus strains known to produce enterotoxins in food.4 Propyl gallate is commonly added to foods to prevent autoxidation and microbial growth.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gravela, E., and Dianzani, M.U. Studies on the mechanism of CCl4-induced polyribosomal damage. FEBS Lett. 9(2), 93-96 (1970).

    2. Gravela, E., Gabriel, L., and Ugazio, G. Protection by glutathione and propyl gallate on the impaired in vitro amino acid incorporation into liver microsomal protein of CCL4 -poisoned rats. Biochem. Pharmacol. 20(8), 2065-2070 (1971).

    3. Kawano, Y., Kawaguchi, M., Hirota, K., et al. Effects of n-propyl gallate on neuronal survival after forebrain ischemia in rats. Resuscitation 83(2), 249-252 (2012).

    4. Fung, D.Y.C., Lin, C.C.S., and Gailani, M.B. Effect of phenolic antioxidants on microbial growth. Crit. Rev. Microbiol. 12(2), 153-183 (1985).