A cucurbitane glycoside antioxidant
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11-oxo MGV

Item No. 22416

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,9β,10α,24R)-24-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-25-hydroxy-9-methyl-19-norlanost-5-en-11-one
CAS Number
126105-11-1
Synonyms
  • 11-oxo Mogroside V
Molecular Formula
C60H100O29
Formula Weight
1285.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC(C)(C)[C@H](O[C@H]1[C@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)O1)CC[C@@H](C)[C@@]4([H])CC[C@@]([C@]4(C)C5)(C)[C@]6([H])CC=C7C(C)(C)[C@@H](O[C@]8([H])O[C@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O9)[C@@H](O)[C@H](O)[C@H]8O)CC[C@@]7([H])[C@]6(C)C5=O
InChi Code
InChI=1S/C60H100O29/c1-23(9-13-35(57(4,5)79)88-55-50(89-54-49(78)43(72)38(67)29(20-63)84-54)45(74)40(69)31(86-55)22-81-52-47(76)42(71)37(66)28(19-62)83-52)24-15-16-58(6)32-12-10-25-26(60(32,8)33(64)17-59(24,58)7)11-14-34(56(25,2)3)87-53-48(77)44(73)39(68)30(85-53)21-80-51-46(75)41(70)36(65)27(18-61)82-51/h10,23-24,26-32,34-55,61-63,65-79H,9,11-22H2,1-8H3/t23-,24-,26-,27-,28-,29-,30-,31-,32+,34+,35-,36-,37-,38-,39-,40-,41+,42+,43+,44+,45+,46-,47-,48-,49-,50-,51-,52-,53+,54+,55+,58+,59-,60+/m1/s1
InChi Key
CGGWHBLPUUKEJC-YMWSYRNLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    11-oxo MGV is a sweet tasting cucurbitane glycoside derivative of mogroside V (Item No. 19853). It has antioxidant effects against both O2- and OH- (EC50s = 4.79 and 16.52 µg/ml, respectively) and prevents OH-induced DNA damage (EC50 = 3.09 µg/ml).1 11-oxo MGV also inhibits carcinogenesis in murine models.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, W.J., Wang, J., and Qi, X.Y. The antioxidant activities of natural sweeteners, mogrosides, from fruits of Siraitia grosvenori. Int. J. Food Sci. Nutr. 58(7), 548-556 (2007).

    2. Takasaki, M., Konoshima, T., Murata, Y., et al. Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori. Cancer Lett. 198(1), 37-42 (2003).