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Diphenhydramine (hydrochloride)

Item No. 22489

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Difenhydramine
  • DPH
Technical Information
Formal Name
2-(diphenylmethoxy)-N,N-dimethyl-ethanamine, monohydrochloride
CAS Number
147-24-0
Molecular Formula
C17H21NO • HCl
Formula Weight
291.8
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
InChi Code
InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChi Key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Diphenhydramine (hydrochloride) (Item No. 22489) is an analytical reference standard that is categorized as an antihistamine.1 It increases hallucinations and manic behavior associated with use of products marketed as bath salts.2 This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 11158).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Thurmond, R.L., Gelfand, E.W., and Dunford, P.J. The role of histamine H1 and H4 receptors in allergic inflammation: The search for new antihistamines. Nat. Rev. Drug Discov. 7(1), 41-53 (2008).

    2. Gunderson, E.W., Kirkpatrick, M.G., Willing, L.M., et al. Intranasal substituted cathinone "bath salts" psychosis potentially exacerbated by diphenhydramine. J. Addict. Med. 7(3), 163-168 (2013).