An internal standard for the quantification of moxifloxacin
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Moxifloxacin-d4 (hydrochloride)

Item No. 22564

Technical Information
Formal Name
1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl-5,5,7,7-d4)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, monohydrochloride
Synonyms
  • BAY 12-8039-d4
Molecular Formula
C21H20D4FN3O4 • HCl
Formula Weight
Purity
≥99% deuterated forms (d1-d4)
A solid
DMF: 3.33 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 0.2 mg/ml
SMILES
O=C1C(C(O)=O)=CN(C2CC2)C3=C1C=C(F)C(N4C([2H])([2H])[C@@]5([H])[C@@](NCCC5)([H])C4([2H])[2H])=C3OC.Cl
InChi Code
InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H/t11-,16+;/m0./s1/i8D2,10D2;
InChi Key
IDIIJJHBXUESQI-RPKOYQESSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Moxifloxacin-d4 is intended for use as an internal standard for the quantification of moxifloxacin (Item No. 14830) by GC- or LC-MS. Moxifloxacin is a fluoroquinolone antibiotic that is active through multiple routes of administration.1 Formulations containing moxifloxacin have been used to treat bacterial infections associated with bronchitis, sinusitis, and other conditions.2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takiff, H., and Guerrero, E. Current prospects for the fluoroquinolones as first-line tuberculosis therapy. Antimicrob. Agents and Chemother. 55(12), 5421-5429 (2011).

    2. Dryden, M.S. Complicated skin and soft tissue infection. J. Antimicrob. Chemother. 65(Suppl 3), iii35-iii44 (2010).

    3. Karageorgopoulos, D.E., Giannopoulou, K.P., Grammatikos, A.P., et alFluoroquinolones compared with β-lactam antibiotics for the treatment of acute bacterial sinusitis: A meta-analysis of randomized controlled trials. Canad. M. A. J. 178(7), 845-854 (2008).

    4. Miravitlles, M. Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 2(3), 191-204 (2007).