A bioactive sphingolipid
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Product Categories

Product Type

Biochemicals
Lipids
Sphingolipids

Research Area

Lipid Biochemistry
Sphingolipids

C30 (ω-hydroxy) Ceramide (d18:1/30:0)

Item No. 22688

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
30-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-triacontanamide
CAS Number
457100-08-2
Synonyms
  • (ω-hydroxy) Ceramide (d18:1/30:0)
  • (ω-hydroxy) Cer(d18:1/30:0)
  • ω-hydroxy-C30 Sphingosine (d18:1/30:0)
  • ω-OH C30 Ceramide (d18:1/30:0)
Molecular Formula
C48H95NO4
Formula Weight
750.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol (5:1): SolubleDMF: SolubleEthanol: Heated
SMILES
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCCCCCCCCCCCCCCCCO)=O)CO
InChi Code
InChI=1S/C48H95NO4/c1-2-3-4-5-6-7-8-24-27-30-33-36-39-42-47(52)46(45-51)49-48(53)43-40-37-34-31-28-25-22-20-18-16-14-12-10-9-11-13-15-17-19-21-23-26-29-32-35-38-41-44-50/h39,42,46-47,50-52H,2-38,40-41,43-45H2,1H3,(H,49,53)/b42-39+/t46-,47+/m0/s1
InChi Key
KSVODRGOBYCXKF-HFBOQBPWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $699

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    Product Description

    C30(ω-hydroxy) Ceramide is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis.1 C30(ω-hydroxy) Ceramide is vital to skin barrier functions and has a role in maturation of epidermis cells of the spermatozoa/testes. C30(ω-hydroxy) Ceramide deficiency causes defective skin-water permeability barrier function and neonatal lethality in elongation of very long chain fatty acids-4 (ELOVL4) deficient mice.2 [Matreya, LLC. Catalog No. 2080]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sandhoff, R. Very long chain sphingolipids: Tissue expression, function and synthesis. FEBS Lett. 584(9), 1907-1913 (2010).

    2. Li, W., Sandhoff, R., Kono, M., et al. Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice. Int. J. Biol. Sci. 3(2):, 120-128 (2007).

    Product Citations

    Nobumoto, W., Naganuma, T., Nozaka, N., et al. Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and composition. The Journal of Biological Chemisty 302(3), 111178 (2026).