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Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.
DOWNLOAD NOWMorantel is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors (nAChRs).1 It enhances channel gating of the α3β2 nAChR subtype by binding to non-canonical sites.2 Formulations containing morantel are used to treat nematode infections in livestock.3
WARNING This product is not for human or veterinary use.
1. Morantel allosterically enhances channel gating of neuronal nicotinic acetylcholine alpha 3 beta 2 receptors. Mol. Pharmacol. 74(2), 466-475 (2008).
2. The positive allosteric modulator morantel binds at noncanonical subunit interfaces of neuronal nicotinic acetylcholine receptors. J. Neurosci. 29(27), 8734-8742 (2009).
3. Pharmacodynamics, pharmacokinetics and faecal persistence of morantel in cattle and goats. J. Vet. Pharmacol. Ther. 16(1), 87-92 (1993).