A prochiral substrate
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Labeling & Detection
Enzyme Substrates

Research Area

3-Hydroxyglutaric Acid dimethyl ester

Item No. 22919

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-hydroxy-pentanedioic acid, 1,5-dimethyl ester
CAS Number
7250-55-7
Synonyms
  • Dimethyl 3-HG
  • Dimethyl β-HG
  • Dimethyl 3-hydroxyglutarate
  • Dimethyl 3-hydroxypentanedioate
  • 3-HG dimethyl ester
  • β-HG dimethyl ester
  • NSC 30047
Molecular Formula
C7H12O5
Formula Weight
176.2
Purity
≥95%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
211 nm
SMILES
O=C(CC(O)CC(OC)=O)OC
InChi Code
InChI=1S/C7H12O5/c1-11-6(9)3-5(8)4-7(10)12-2/h5,8H,3-4H2,1-2H3
InChi Key
CUPGMRSSZADEIW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $29

    Add

    5 g

    $79

    Add

    10 g

    $141

    Add

    25 g

    $281

    Add
    Product Description

    3-Hydroxyglutaric acid dimethyl ester is a prochiral substrate and an esterified derivative of 3-hydroxyglutaric acid (Item No. 16334).1 3-Hydroxyglutaric acid dimethyl ester was used to characterize the ability of a lipase from C. antarctica to catalyze aminolysis of prochiral substrates, a process commonly utilized in the biosynthesis of statins.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Puertas, S., Rebolledo, F., and Gotor, V. Enantioselective enzymatic aminolysis and ammonolysis of dimethyl 3-hydroxyglutarate. Synthesis of (R)-4-amino-3-hydroxybutanoic acid. The Journal of Organic Chemistry 61(17), 6024-6027 (1996).