A broad-spectrum antipicornaviral agent
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Pirodavir

Item No. 22922

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoic acid, ethyl ester
CAS Number
124436-59-5
Synonyms
  • R-77975
Molecular Formula
C21H27N3O3
Formula Weight
369.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
257 nm
SMILES
CCOC(C1=CC=C(OCCC2CCN(C3=CC=C(C)N=N3)CC2)C=C1)=O
InChi Code
InChI=1S/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3
InChi Key
KCHIOGFOPPOUJC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Cayman Chemical
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    Product Description

    Pirodavir is a broad-spectrum antipicornaviral agent.1 It is active against 80 typed (MICs = 0.001-14.4 µg/ml) and one untyped rhinovirus strain (MIC = 0.002 µg/ml) and is active against both group A and group B serotypes. It is also active against serotypes of coxsackievirus, poliovirus, and echovirus enteroviruses (MICs = 0.018-8.5, 0.025-0.27, and 0.019-1.3 µg/ml, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Andries, K., Dewindt, B., Snoeks, J., et al. In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity. Antimicrob. Agents Chemother. 36(1), 100-107 (1992).