An Analytical Reference Standard
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Exempt Preparation(s)
43518Perampanel (exempt preparation)
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Perampanel

Item No. 23003

Restricted Product (Schedule III)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(1',6'-dihydro-6'-oxo-1'-phenyl[2,3'-bipyridin]-5'-yl)-benzonitrile
CAS Number
380917-97-5
Molecular Formula
C23H15N3O
Formula Weight
349.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: >1 mg/mlChloroform: slightly solubleDMSO: slightly soluble
λmax
295, 347 nm
SMILES
O=C1N(C2=CC=CC=C2)C=C(C3=CC=CC=N3)C=C1C4=C(C#N)C=CC=C4
InChi Code
InChI=1S/C23H15N3O/c24-15-17-8-4-5-11-20(17)21-14-18(22-12-6-7-13-25-22)16-26(23(21)27)19-9-2-1-3-10-19/h1-14,16H
InChi Key
PRMWGUBFXWROHD-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
III
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Perampanel (Item No. 23003) is an analytical reference standard categorized as an anticonvulsant.1 Perampanel has a potential for abuse.2 Formulations containing perampanel have been used in the treatment of epilepsy.2 Perampanel is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanada, T., Hashizume, Y., Tokuhara, N., et al. Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia 52(7), 1331-1340 (2011).

    2. Hawkins, K.L., and Gidal, B.E. When adverse effects are seen as desirable: Abuse potential of the newer generation antiepileptic drugs. Epilepsy Behav. 77, 62-72 (2017).