A nucleoside triphosphate
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Inosine 5'-triphosphate (sodium salt)

Item No. 23063

Technical Information
Formal Name
inosine 5'-(tetrahydrogen triphosphate), trisodium salt
CAS Number
35908-31-7
Synonyms
  • ITP
  • NSC 20266
Molecular Formula
C10H12N4O14P3 • 3Na
Formula Weight
Purity
≥95%
A crystalline solid
PBS (pH 7.2): 10 mg/ml
λmax
249 nm
SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CNC3=O)O[C@@H]1COP(OP(OP(O)([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
InChi Key
QRGLCGLOQVQVCS-MSQVLRTGSA-K
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Inosine 5'-triphosphate (ITP) is a nucleoside triphosphate that functions as an alternative substrate for ATPases and GTPases.1,2 It has been used to study activation and binding kinetics of nucleoside interaction with various ATPases and GTPases.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanson, R.L., and Kennedy, E.P. Energy-transducing adenosine triphosphatase from Escherichia coli: Purification, properties, and inhibition by antibody. J. Bacteriol. 114(2), 772-781 (1973).

    2. Pieper, U., Schweitzer, T., Groll, D.H., et alThe GTP-binding domain of McrB: More than just a variation on a common theme? J. Mol. Biol. 292(3), 547-556 (1999).