A fluorescently tagged sphingolipid
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C6 NBD Glucosylceramide (d18:1/6:0)

Item No. 23209

Technical Information
Formal Name
N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-hexanamide
CAS Number
94885-03-7
Synonyms
  • C6 NBD Glucosylceramide
  • NBD GlcCer(d18:1/6:0)
  • NBD GluCer(d18:1/6:0)
  • NBD Glucosylceramide (d18:1/6:0)
  • N-hexanoyl-NBD-Glucosylceramide
Molecular Formula
C36H59N5O11
Formula Weight
Purity
≥98%
A solid
Chloroform:Methanol (5:1): SolubleChloroform:Methanol (5:1): solubleMethanol: Soluble
SMILES
O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCNC2=CC=C([N+]([O-])=O)C3=NON=C23)=O)[C@@H]1O
InChi Code
InChI=1S/C36H59N5O11/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-28(43)26(24-50-36-35(47)34(46)33(45)29(23-42)51-36)38-30(44)19-16-14-17-22-37-25-20-21-27(41(48)49)32-31(25)39-52-40-32/h15,18,20-21,26,28-29,33-37,42-43,45-47H,2-14,16-17,19,22-24H2,1H3,(H,38,44)/b18-15+/t26-,28+,29+,33+,34-,35+,36+/m0/s1
InChi Key
ZYEQNDHFYIPTAY-YAIFWNLCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    C6 NBD glucosylceramide (d18:1/6:0) is a biologically active derivative of glucosylceramide that is tagged with a fluorescent C-6 nitrobenzoxadiazole (C-6 NBD; Item No. 18871) group.1,2 C6 NBD glucosylceramide (d18:1/6:0) has been used to study the metabolism and internalization of glucosylceramide. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1622]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kok, J.W., Babia, T., Klappe, K., et alFluorescent, short-chain C6-NBD-sphingomyelin, but not C6-NBD-glucosylceramide, is subject to extensive degradation in the plasma membrane: Implications for signal transduction related to cell differentiation. Biochem. J. 309(Pt 3), 905-912 (1995).

    2. Tomás, M., Durán, J.M., Lázaro-Diéguez, F., et alFluorescent analogues of plasma membrane sphingolipids are sorted to different intracellular compartments in astrocytes; Harmful effects of chronic ethanol exposure on sphingolipid trafficking and metabolism. FEBS Lett. 563(1-3), 59-65 (2004).