An internal standard for the quantification of 1-β-D-glucosylsphingosine
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13C6 Glucosylsphingosine (d18:1)

Item No. 23212

Technical Information
Formal Name
2S-amino-3R-hydroxy-4E-octadecen-1-yl, β-D-glucopyranoside-1,2,3,4,5,6-13C6
CAS Number
299172-48-8
Synonyms
  • 1-β-D-Glucosyl-1,2,3,4,5,6-13C6-sphingosine
  • 13C6-Glucosylsphingosine
Molecular Formula
C18[13C]6H47NO7
Formula Weight
Purity
≥98%
Formulation
A solid
Chloroform:Methanol (2:1): solubleEthanol: solubleMethanol: soluble
SMILES
O[13C@@H]1[13C@@H](O)[13C@H](O)[13C@@H]([13CH2]O)O[13C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)N
InChi Code
InChI=1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21+,22-,23+,24+/m0/s1/i16+1,20+1,21+1,22+1,23+1,24+1
InChi Key
HHJTWTPUPVQKNA-DBGPLVPSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) (Item No. 23211) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.1,2 [Matreya, LLC. Catalog No. 2209]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Murugesan, V., Chuang, W.-L., Liu, J., et alGlucosylsphingosine is a key biomarker of Gaucher disease. Am. J. Hematol. 91(11), 1082-1089 (2016).

    2. Schueler, U.H., Kolter, T., Kaneski, C.R., et alToxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: A model system for assessing neuronal damage in Gaucher disease type 2 and 3. Neurobiol. Dis. 14(3), 595-601 (2003).