A C-terminal fragment of a neurotoxin
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Tetanus Toxin C-Fragment from Clostridium tetani

Item No. 23222

Technical Information
MW
~50,000 Da
Each vial, when reconstituted with 50 µl of sterile purified water, contains 10 µg of tetanus toxin C-fragment in 0.01 M sodium phosphate, pH 7.5
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Tetanus toxin C-fragment from C. tetani is the C-terminal end of tetanus toxin that binds to gangliosides on presynaptic terminals at the neuromuscular junction, allowing tetanus toxin to be taken up into neurons.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Montecucco, C., Schiavo, F., Poulain, B., et alTetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. EMBO J. 11(10), 3577-3583 (2016).