An intermediate in the biosynthesis of erythromycin
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Erythromycin C

Item No. 23478

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3''-O-demethyl-erythromycin
CAS Number
1675-02-1
Molecular Formula
C36H65NO13
Formula Weight
719.9
Purity
≥85%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: solubleWater: limited solubility
SMILES
C[C@H]1[C@H](O)[C@@](O)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]([C@H](O)[C@H]2C)(O)C)=O)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C2=O)([H])O1
InChi Code
InChI=1S/C36H65NO13/c1-13-24-36(10,45)29(40)19(4)26(38)17(2)15-35(9,44)31(50-33-27(39)23(37(11)12)14-18(3)46-33)20(5)28(21(6)32(42)48-24)49-25-16-34(8,43)30(41)22(7)47-25/h17-25,27-31,33,39-41,43-45H,13-16H2,1-12H3/t17-,18-,19+,20+,21-,22+,23+,24-,25+,27-,28+,29-,30+,31-,33+,34-,35-,36-/m1/s1
InChi Key
MWFRKHPRXPSWNT-QNPWSHAKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Erythromycin C is an intermediate in the biosynthesis of erythromycin (Item No. 16486).1 It is also a potential impurity found in commercial preparations of erythromycin. Erythromycin C is half as active or less than erythromycin A or B against most Gram-positive and Gram-negative bacteria tested.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chen, Y., Deng, W., Wu, J., et al. Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation. Appl. Environ. Microbiol. 74(6), 1820-1828 (2008).

    2. Kibwage, I.O., Hoogmartens, J., Roets, E., et al. Antibacterial activities of erythromycins A, B, C, and D and some of their derivatives. Antimicrob. Agents Chemother. 28(5), 630-633 (1985).