An antiviral active against lipid envelope-containing viruses
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Docosanol

Item No. 23793

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-docosanol
CAS Number
661-19-8
Synonyms
  • Behenyl Alcohol
  • n-Docosanol
  • Docosyl Alcohol
  • FOH22:0
  • NSC 8407
Molecular Formula
C22H46O
Formula Weight
326.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 1.7 mg/ml
SMILES
CCCCCCCCCCCCCCCCCCCCCCO
InChi Code
InChI=1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
InChi Key
NOPFSRXAKWQILS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 g

    $41

    Add

    100 g

    $72

    Add

    250 g

    $167

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Docosanol is an aliphatic alcohol that has broad-spectrum antiviral activity against viruses with a lipid envelope (ID50s = 3-12 nM for inhibition of replication).1 It inhibits herpes simplex virus type 1 (HSV-1) replication and protein synthesis in Vero cells.2 It also inhibits HSV-2 plaque formation and virus production in wild-type Vero cells and cells resistant to acyclovir (Item No. 14160). Docosanol acts by prohibiting the HSV envelope from fusing with the plasma membrane.1 Formulations containing docosanol have been used in the topical treatment of HSV-1.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pope, L.E., Marcelletti, J.F., Katz, L.R., et al. The anti-herpes simplex virus activity of n-docosanol includes inhibition of the viral entry process. Antiviral Res. 40(1-2), 85-94 (1998).

    2. Katz, D.H., Marcelletti, J.F., Khalil, M.H., et al. Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex. Proc. Natl. Acad. Sci. USA 88(23), 10825-10829 (1991).