A synthetic corticosteroid
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Amcinonide

Item No. 23903

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(11β,16α)-21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
CAS Number
51022-69-6
Synonyms
  • CL 34,699
Molecular Formula
C28H35FO7
Formula Weight
502.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 25 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlEthanol: 10 mg/ml
λmax
236.00 nm
SMILES
O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@]5([H])[C@@]4(C(COC(C)=O)=O)OC6(CCCC6)O5)=C1
InChi Code
InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1
InChi Key
ILKJAFIWWBXGDU-MOGDOJJUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $37

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    100 mg

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    250 mg

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    500 mg

    $235

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    Product Description

    Amcinonide is a synthetic corticosteroid.1 Topical administration of amcinonide reduces inflammation in rat models of carrageenan-induced plantar edema and air pouch granulomas (ID50s = 1.85 and 4.2 mg/kg, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wepierre, J., and Bogaievsky, Y. Comparative pharmacological activity of triamcinolone acetonide and of a new topical steroid: Amcinonide, after percutaneous or oral administration (author’s transl). J. Pharmacol. 11(4), 449-462 (1980).