An antibiotic complex
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Parvodicin Complex

Item No. 24036

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
187888-13-7
Molecular Formula
C83H88Cl2N8O29 (for C1)
Formula Weight
1732.5
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O[C@@H]([C@H](O)[C@@H](CO[R1])O1)[C@H](O)[C@H]1OC2=CC(O)=CC([C@@H](C(O)=O)NC([C@@]([C@@H](C3=CC(Cl)=C(OC4=CC5=CC(OC6=CC=C7C=C6)=C4O[C@H]8[C@H](N[R])[C@@H](O)[C@H](O)[C@@H](C(O)=O)O8)C=C3)O)([H])NC9=O)=O)=C2C%10=C(O)C=CC([C@@]9([H])NC([C@]5([H])NC([C@@](C%11=C(Cl)C(O)=CC(OC%12=C(O)C=CC%13=C%12)=C%11)([H])NC([C@](C7)([H])NC([C@@H]%13NC)=O)=O)=O)=O)=C%10.CC(CCCCCCCCC)=O.CC(CCCCCCCC(C)C)=O.CC(CCCCCCCCCC)=O.CC(CCCCCCCCC(C)C)=O.CC(CCCCCCCCCCC)=O.CC(CCCCCCCCC(C)C)=O.CC(CCCCCCCCCCC)=O.[H]C.[H]C.[H]C.[H]
InChi Code
InChI=1S/2C85H90Cl2N8O30.2C83H88Cl2N8O29.2C82H86Cl2N8O29.C81H84Cl2N8O29/c1-34(2)11-9-7-5-6-8-10-12-58(101)90-67-70(104)72(106)75(83(116)117)125-84(67)124-74-55-27-40-28-56(74)121-52-22-17-39(25-47(52)86)68(102)66-81(113)94-65(82(114)115)45-29-41(97)30-54(122-85-73(107)71(105)69(103)57(123-85)33-118-35(3)96)59(45)44-24-37(15-20-49(44)98)62(78(110)95-66)91-79(111)63(40)92-80(112)64-46-31-43(32-51(100)60(46)87)120-53-26-38(16-21-50(53)99)61(88-4)77(109)89-48(76(108)93-64)23-36-13-18-42(119-55)19-14
InChi Key
FDOGLPXOSZWYQW-GHEVLMKASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Parvodicin complex is a mixture of closely related lipophilic glycopeptides originally isolated from A. parvosata.1 The parvodicin complex has activity against Gram-positive bacteria (MICs = 0.8-12.5 µg/ml) including methicillin-resistant strains of S. aureus (MRSA), S. hemolyticus, and E. faecalis (MICs = 0.1-25 µg/ml). Glycopeptide antibiotics act by preventing cell wall synthesis by binding and sequestering a cell wall precursor with a D-alanine-containing peptide.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Christensen, S.B., Allaudeen, H.S., Burke, M.R., et al. Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidation. J. Antibiot. (Tokyo) 40(7), 970-990 (1987).

    2. Somma, S., Gastaldo, L., and Corti, A. Teicoplanin, a new antibiotic from Actinoplanes teichomyceticus nov. sp. Antimicrob. Agents Chemother. 26(6), 917-923 (1984).