A cytotoxic Streptomyces metabolite
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Resistoflavine

Item No. 24178

Technical Information
Formal Name
(-)-3,5,7,11b-tetrahydroxy-1,1,9-trimethyl-2H-benzo[cd]pyrene-2,6,10(1H,11bH)-trione
CAS Number
29706-96-5
Molecular Formula
C22H16O7
Formula Weight
Purity
≥98%
A solid
DMF: SolubleDMSO: Soluble
SMILES
CC1=CC(O)=C(C(C(C(O)=CC(O)=C2C(C3(C)C)=O)=C2C4(O)C3=C5)=O)C4=C1C5=O
InChi Code
InChI=1S/C22H16O7/c1-7-4-8(23)14-17-13(7)11(26)6-12-21(2,3)20(28)16-10(25)5-9(24)15(19(14)27)18(16)22(12,17)29/h4-6,23-25,29H,1-3H3
InChi Key
FRXZTKQCZPGFDX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Resistoflavine is a metabolite of the marine actinomycete S. chibaensis.1 It slows the growth of and is cytotoxic to HMO2 and HepG2 cells with mean lethal concentrations (LC50) of 0.013 and 0.016 µg/ml, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gorajana, A., Venkatesan, M., Vinjamuri, S., et alResistoflavine, cytotoxic compound from a marine actinomycete, Streptomyces chibaensis AUBN1/7. Microb. Res. 162(4), 322-327 (2007).