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Item No. 24381

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3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) (Item No. 24380). 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1 [Matreya, LLC. Catalog No. 1891]
WARNING This product is not for human or veterinary use.
1. Characterization of serine palmitoyltransferase in normal human tissues. J. Histochem. Cytochem. 51(5), 687-696 (2003).