A naturally occurring ceramide
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C19 Ceramide (d18:1/19:0)

Item No. 24395

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-nonadecanamide
CAS Number
67492-17-5
Synonyms
  • Cer(d18:1/19:0)
  • Ceramide (d18:1/19:0)
  • N-nonadecanoyl-D-erythro-Sphingosine
Molecular Formula
C37H73NO3
Formula Weight
580.0
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleEthanol: WarmedMethanol: Warmed
SMILES
OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C37H73NO3/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-33-37(41)38-35(34-39)36(40)32-30-28-26-24-22-20-16-14-12-10-8-6-4-2/h30,32,35-36,39-40H,3-29,31,33-34H2,1-2H3,(H,38,41)/b32-30+/t35-,36+/m0/s1
InChi Key
SNMLDULQFHAZRC-RQDJVNCUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.1,2,3 It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.2 C19 Ceramide is also increased in mouse hearts following administration of angiotensin II (Item No. 17150).3 [Matreya, LLC. Catalog No. 2039]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Krishna, N., Muralidhar, P., Kumar, M.M., et al. A new sphingolipid from the gorgonian Junceella juncea of the Indian ocean. Nat. Prod. Res. 18(6), 551-555 (2004).

    2. Roux, A., Muller, L., Jackson, S.N., et al. Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents. ACS Chem Neurosci. 6(2), 247-259 (2015).

    3. Glenn, D.J., Cardema, M.C., Ni, W., et al. Cardiac steatosis potentiates angiotensin II effects in the heart. Am. J. Physiol. Heart Circ. Physiol. 308(4), H339-350 (2015).