A naturally occurring ceramide
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C18:1 Ceramide (d18:1/18:1(9Z))

Item No. 24397

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-9Z-octadecenamide
CAS Number
5966-28-9
Synonyms
  • Cer(d18:1/18:1(9Z))
  • C18:1 Ceramide
  • Ceramide (d18:1/18:1(9Z))
  • N-Octadecenoyl-(cis-9)-D-erythro-Sphingosine
Molecular Formula
C36H69NO3
Formula Weight
563.9
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleDMF: 0.1 mg/ml
SMILES
OC[C@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC
InChi Code
InChI=1S/C36H69NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,29,31,34-35,38-39H,3-16,19-28,30,32-33H2,1-2H3,(H,37,40)/b18-17-,31-29+/t34-,35+/m0/s1
InChi Key
OBFSLMQLPNKVRW-RHPAUOISSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $107

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    Product Description

    C18:1 Ceramide is a naturally occurring ceramide.1,2,3 Levels of C18:1 ceramide are elevated in overweight and insulin-resistant mice and cattle.1,2 C18:1 Ceramide is also increased in the plasma and ovarian tissue of patients with advanced ovarian cancer.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sajan, M.P., Ivey, R.A., Lee, M.C., et al. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation. J. Lipid Res. 56(1), 70-80 (2015).

    2. Rico, J.E., Bandaru, V.V., Dorskind, J.M., et al. Plasma ceramides are elevated in overweight Holstein dairy cows experiencing greater lipolysis and insulin resistance during the transition from late pregnancy to early lactation. J. Dairy Sci. 98(11), 7757-7770 (2015).

    3. Knapp, P., Bodnar, L., Błachnio-Zabielska, A., et al. Plasma and ovarian tissue sphingolipids profiling in patients with advanced ovarian cancer. Gynecol. Oncol. 147(1), 139-144 (2017).