An internal standard for the quantification of C18 galactosylceramide
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C18 Galactosylceramide-d35 (d18:1/18:0-d35)

Item No. 24467

Technical Information
Formal Name
N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]-octadecanamide-d35
CAS Number
145176-92-7
Synonyms
  • Galactosylceramide (d18:1/18:0-d35)
  • GalCer(d18:1/18:0-d35)
  • N-octadecanoyl Psychosine-d35
Molecular Formula
C42H46D35NO8
Formula Weight
Purity
≥99% deuterated forms (d1-d35)
Formulation
A solid
Chloroform: solubleChloroform:Methanol (2:1): solubleEthanol: heated
SMILES
O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O
InChi Code
InChI=1S/C42H81NO8/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-38(46)43-35(34-50-42-41(49)40(48)39(47)37(33-44)51-42)36(45)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,35-37,39-42,44-45,47-49H,3-28,30,32-34H2,1-2H3,(H,43,46)/b31-29+/t35-,36+,37+,39-,40-,41+,42+/m0/s1/i1D3,3D2,5D2,7D2,9D2,11D2,13D2,15D2,17D2,18D2,20D2,22D2,24D2,26D2,28D2,30D2,32D2
InChi Key
YMYQEDCYNANIPI-CLKFQYKCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    C18 Galactosylceramide-d35 is intended for use as an internal standard for the quantification of C18 galactosylceramide by GC- or LC-MS. C18 Galactosylceramide is a naturally occurring sphingolipid that has been found in the cerebellum of rats and humans.1,2 It is selectively localized with cholesterol over potassium, sodium, or phosphocholine in rat cerebellum white matter.1 [Matreya, LLC. Catalog No. 1914]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Börner, K., Nygren, H., Hagenhoff, B., et alDistribution of cholesterol and galactosylceramide in rat cerebellar white matter. Biochim. Biophys. Acta 1761(3), 335-344 (2006).

    2. Boutin, M., Sun, Y., Shacka, J.J., et alTandem mass spectrometry multiplex analysis of glucosylceramide and galactosylceramide isoforms in brain tissues at different stages of Parkinson Disease. Anal. Chem. 88(3), 1856-1863 (2016).