A cell-permeable fluorescent sodium indicator
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

ING-2 AM

Item No. 24489

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-[(acetyloxy)methoxy]-4,5-dichloro-9-[3-methoxy-4-[13-(2-methoxy-4-methylphenyl)-1,4,10-trioxa-7,13-diazacyclopentadec-7-yl]phenyl]-3-oxo-3H-xanthene-2,7-dipropanoic acid, 2,7-bis[(acetyloxy)methyl] ester
CAS Number
1642554-49-1
Synonyms
  • ANG-2 Acetoxymethyl ester
  • ANG-2 AM
  • Asante Natrium Green-2 Acetoxymethyl ester
  • Asante Natrium Green-2 AM
  • ING-2 Acetoxymethyl ester
  • ION Natrium Green-2 Acetoxymethyl ester
  • ION Natrium Green-2 AM
Molecular Formula
C53H60Cl2N2O18
Formula Weight
1084.0
Purity
≥90%
Emission
545 nm
Excitation
525 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
O=C(C)OCOC(CCC1=CC2=C(C3=CC(OC)=C(N4CCOCCOCCN(C5=C(OC)C=C(C)C=C5)CCOCC4)C=C3)C6=CC(CCC(OCOC(C)=O)=O)=C(OCOC(C)=O)C(Cl)=C6OC2=C(C1=O)Cl)=O
InChi Code
InChI=1S/C53H60Cl2N2O18/c1-32-7-11-41(43(25-32)64-5)56-15-19-66-20-16-57(18-22-68-24-23-67-21-17-56)42-12-8-36(28-44(42)65-6)47-39-26-37(9-13-45(61)72-29-69-33(2)58)50(63)48(54)52(39)75-53-40(47)27-38(10-14-46(62)73-30-70-34(3)59)51(49(53)55)74-31-71-35(4)60/h7-8,11-12,25-28H,9-10,13-24,29-31H2,1-6H3
InChi Key
OTIAVQNFWAJQKZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 x 50 µg

    $478

    Add

    500 µg

    $478

    Add
    Product Description

    ING-2 AM is a cell-permeable fluorescent sodium indicator.1 It binds to sodium (Kd = 20 mM) and displays excitation/emission maxima of 525 and 545 nm, respectively. ING-2 AM has been used to kinetically monitor sodium levels in isolated human platelets via flow cytometry.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aliotta, A., Calderara, D.B., and Alberio, L. Flow cytometric monitoring of dynamic cytosolic calcium, sodium, and potassium fluxes following platelet activation. Cytometry A. 97(9), 933-944 (2020).