A hydroxy fatty acid
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2-hydroxy Stearic Acid

Item No. 24590

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-hydroxy-octadecanoic acid
CAS Number
629-22-1
Synonyms
  • NSC 907
  • (±)-α-hydroxy Octadecanoic Acid
  • (±)-α-hydroxy Stearic Acid
Molecular Formula
C18H36O3
Formula Weight
300.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol (5:1): Soluble
SMILES
CCCCCCCCCCCCCCCCC(O)C(O)=O
InChi Code
InChI=1S/C18H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h17,19H,2-16H2,1H3,(H,20,21)
InChi Key
KIHBGTRZFAVZRV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $59

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    25 mg

    $112

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    50 mg

    $208

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    Product Description

    2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana.1,2,3 It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM.4 Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease.2,3 [Matreya, LLC. Catalog No. 1707]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kendel, M., Wielgosz-Collin, G., Bertrand, S., et al. Lipid composition, fatty acids and sterols in the seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): An analysis from nutritional, chemotaxonomic, and antiproliferative activity perspectives. Mar. Drugs 13(9), 5606-5628 (2015).

    2. Leimer, E.M., Pappan, K.L., Nettles, D.L., et al. Lipid profile of human synovial fluid following intra-articular ankle fracture. J. Orthop. Res. 35(3), 657-666 (2017).

    3. Niang, F., Sarfo, F.S., Frimpong, M., et al. Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease. Sci. Rep. 5:17693, (2015).

    4. Kusmoto, K., Kageyama, K., Matsuda, T., et al. Effects of ethyl-esterization, chain-lengths, unsaturation degrees, and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids. Exp. Oncol. 29(2), 106-110 (2007).