A hydroxy fatty acid
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Isomer(s)
2849412-hydroxy Lauric Acid
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3-hydroxy Lauric Acid

Item No. 24642

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-hydroxy-dodecanoic acid
CAS Number
1883-13-2
Synonyms
  • (±)-3-hydroxy Dodecanoic Acid
  • (±)-β-hydroxy Dodecanoic Acid
  • FA 12:0;O
  • (±)-β-hydroxy Lauric Acid
Molecular Formula
C12H24O3
Formula Weight
216.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: SolubleMethanol: Soluble
λmax
212 nm
SMILES
CCCCCCCCCC(O)CC(O)=O
InChi Code
InChI=1S/C12H24O3/c1-2-3-4-5-6-7-8-9-11(13)10-12(14)15/h11,13H,2-10H2,1H3,(H,14,15)
InChi Key
MUCMKTPAZLSKTL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $94

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    25 mg

    $196

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    50 mg

    $366

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    Product Description

    3-hydroxy Lauric acid is a hydroxylated fatty acid that is found in bacteria as well as Pseudosuberites and D. calyx sea sponges.1,2,3,4 It has antifungal activity against a panel of seven fungi (MICs = 10-50 μg/ml).3 3-hydroxy Lauric acid acts as a partial agonist of GPR84 receptors in vitro (EC50 = 5.24 μM).5 [Matreya, LLC. Catalog No. 1731]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, M.C., Pak, S.H., Rim, S.G., et al. Luteolibacter arcticus sp. nov., isolated from high Arctic tundra soil, and emended description of the genus Luteolibacter. Int. J. Syst. Evol. Microbiol. 65(Pt. 6), 1922-1928 (2015).

    2. Panda, S., Bandyopadhyay, P.K., and Chatterjee, S.N. Characterization of Pseudomonas aeruginosa PB112 (JN996498) isolated from infected Labeo bata (Hamilton) by 16S rRNA gene sequence analysis and fatty acid methyl ester (FAME) analysis. African J. Biotechnol. 12(4), 400-405 (2013).

    3. He, R., Wakimoto, T., Egami, Y., et al. Heterologously expressed β-hydroxyl fatty acids from a metagenomic library of a marine sponge. Bioorg. Med. Chem. Lett. 22(24), 7322-7325 (2012).

    4. Barnathan, G., Kornprobst, J.-M., Doumenq, P., et al. Sponge fatty acids, 5. Characterization of complete series of 2-hydroxy long-chain fatty acids in phospholipids of two Senegalese marine sponges from the family suberitidae: Pseudosuberites sp. and Suberites massa. J. Nat. Prod. 56(12), 2104-2113 (2004).

    5. Kaspersen, M.H., Jenkins, L., Dunlop, J., et al. Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4, and GPR84. Med. Chem. Commun. 8(6), 1360-1365 (2017).