An inhibitor of MMP-1, MMP-2, and MMP-3
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MMP Inhibitor I (trifluoroacetate salt)

Item No. 24708

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(S)-1-((2-aminobenzoyl)glycyl)-N-((R)-1-(((R)-1-(hydroxyamino)-1-oxopropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide, trifluoroacetate salt
Synonyms
  • Abz-GP-DLeu-DAla-NH-OH
  • FN 439
  • Matrix Metalloproteinase Inhibitor I
Molecular Formula
C23H35N6O6 • XCF3COOH
Formula Weight
491.6
Purity
≥95%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
CC(C)C[C@H](C(N[C@H](C)C(NO)=O)=O)NC([C@H]1N(C(CNC(C2=C(N)C=CC=C2)=O)=O)CCC1)=O.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C23H34N6O6.C2HF3O2/c1-13(2)11-17(22(33)26-14(3)20(31)28-35)27-23(34)18-9-6-10-29(18)19(30)12-25-21(32)15-7-4-5-8-16(15)24;3-2(4,5)1(6)7/h4-5,7-8,13-14,17-18,35H,6,9-12,24H2,1-3H3,(H,25,32)(H,26,33)(H,27,34)(H,28,31);(H,6,7)/t14-,17-,18+;/m1./s1
InChi Key
GPSGGQYPYRTZQT-WQYGLUBDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $81

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    1 mg

    $152

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    Product Description

    MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively).1 It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Odake, S., Morita, Y., Morikawa, T., et al. Inhibition of matrix metalloproteinases by peptidyl hydroxamic acids. Biochem. Biophys. Res. Commun. 199(3), 1442-1446 (1994).