An N-terminal fragment of NPY
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Neuropeptide Y (1-24) (human, rat) (trifluoroacetate salt)

Item No. 24715

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • NPY (1-24) (human, rat)
Molecular Formula
C116H170N30O40S • XCF3COOH
Formula Weight
2656.8
Purity
≥95%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(CNC([C@@H]2CCCN2C([C@H](CC(N)=O)NC([C@@H](NC([C@@H]3CCCN3C([C@H](CCCCN)NC([C@H](CO)NC([C@@H]4CCCN4C([C@@H](N[H])CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)C)=O)=O)C)=O)=O)CC(O)=O)=O)CCSC)=O)C)=O)=O)CC6=CC=C(O)C=C6)=O)CC7=CC=C(O)C=C7)=O)=O)C)=O)=O.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C116H170N30O40S.C2HF3O2/c1-56(2)45-73(93(120)164)134-96(167)58(4)126-106(177)80(54-147)141-103(174)75(48-63-25-31-66(151)32-26-63)136-102(173)74(47-62-23-29-65(150)30-24-62)135-98(169)68(16-10-39-123-116(121)122)130-94(165)57(3)125-97(168)71(37-44-187-7)132-104(175)77(51-91(160)161)138-100(171)70(34-36-89(156)157)131-95(166)59(5)127-109(180)83-18-12-40-143(83)112(183)60(6)128-101(172)76(50-90(158)159)137-99(170)69(33-35-88(154)155)129-87(153)53-124-108(179)82-17-11-42-145(82)115(186)79(49-86(119)152)140-105(176)78(52-92(162)163)139-110(181)85-20-14-43-146(85)114(185)72(15-8-9-38-117)133-107(178)81(55-148)142-111(182)84-19-13-41-144(84)113(184)67(118)46-61-21-27-64(149)28-22-61;3-2(4,5)1(6)7/h21-32,56-60,67-85,147-151H,8-20,33-55,117-118H2,1-7H3,(H2,119,152)(H2,120,164)(H,124,179)(H,125,168)(H,126,177)(H,127,180)(H,128,172)(H,129,153)(H,130,165)(H,131,166)(H,132,175)(H,133,178)(H,134,167)(H,135,169)(H,136,173)(H,137,170)(H,138,171)(H,139,181)(H,140,176)(H,141,174)(H,142,182)(H,154,155)(H,156,157)(H,158,159)(H,160,161)(H,162,163)(H4,121,122,123);(H,6,7)/t57-,58-,59-,60-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-;/m0./s1
InChi Key
KIYUXZYPXHBHMM-NIEXQDNRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $90

    Add

    1 mg

    $169

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Neuropeptide Y (NPY) (1-24) is an N-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.1 NPY (1-24) does not inhibit [3H]-NPY binding in rat CNS membranes at concentrations up to 10 µM and has no effect on the twitch response of isolated rat vas deferens either alone (EC50 = >1 µM) or when used in combination with the C-terminal fragment NPY (25-36) at a concentration of 1 µM.2,3 NPY (1-24) stimulates histamine release from isolated rat peritoneal mast cells with a lower efficacy than full length NPY.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balasubramaniam, A. Neuropeptide Y family of hormones: Receptor subtypes and antagonists. Peptides 18(3), 445-457 (1997).

    2. Martel, J.-C., Fournier, A., St-Pierre, S., et al. Comparative structural requirements of brain neuropeptide Y binding sites and vas deferens neuropeptide Y receptors. Mol. Pharmacol. 38(4), 494-502 (1990).

    3. Kahl, U., Langel, Ü., Bartfai, T., et al. Functional effects and ligand binding of chimeric galanin-neuropeptide Y (NPY) peptides on NPY and galanin receptor types. Br. J. Pharmacol. 111(4), 1129-1134 (1994).

    4. Grundemar, L., Krstenansky, J.L., and Håkanson, R. Neuropeptide Y and truncated neuropeptide Y analogs evoke histamine release from rat peritoneal mast cells. A direct effect on G proteins? Eur. J. Pharmacol. 258(1-2), 163-166 (1994).