A sphingolipid
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Ceramide (hydroxy) (bovine spinal cord)

Item No. 24834

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Molecular Formula
C36H71NO4 (for 2-hydroxy stearoyl)
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol (2:1): SolubleMethanol: Soluble
SMILES
O=C(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO)C(CCCCCCCCCCCCCCCC)O
InChi Code
InChI=1S/C36H71NO4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(40)36(41)37-33(32-38)34(39)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-35,38-40H,3-27,29,31-32H2,1-2H3,(H,37,41)/b30-28+/t33-,34+,35?/m0/s1
InChi Key
ZNZKGWLGVHSOIV-LVTSMTQESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $149

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    50 mg

    $481

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    Product Description

    Ceramides are generated from sphingomyelin (Item Nos. 22674 | 24345) through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.1 This product contains ceramide molecular species with primarily 2-hydroxy C24:0 and 2-hydroxy C18:0 fatty acyl chains. [Matreya, LLC. Catalog No. 1323]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ogretmen, B., Pettus, B.J., Rossi, M.J., et al. Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A547 human lung adenocarcinoma cell line. The Journal of Biological Chemisty 277(15), 12960-12969 (2002).