An affinity probe for ganglioside GM1 binding partners
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C6 Biotin Ganglioside GM1 (d18:1/6:0)

Item No. 24840

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,4S,5R,6R)-5-acetamido-2-(((2R,3S,4R,5R,6S)-3-(((2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-(((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-(((2S,3R,E)-3-hydroxy-2-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)octadec-4-en-1-yl)oxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-5-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
Synonyms
  • Biotin-C6:0-GM1
  • N-hexanoyl-Biotin-Monosialoganglioside GM1
Molecular Formula
C71H122N6O33S
Formula Weight
1619.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol:Water (2:1:0.1): soluble
SMILES
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@]2([H])[C@@H]([C@@]([C@H]([C@H](O2)CO)O[C@]3([H])O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O[C@@]4([H])[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)CO)([H])O[C@]5(C(O)=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@@H]([C@H](O)CO)O)O5)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCNC(CCCC[C@@H]6SC[C@@](N7)([H])[C@]6([H])NC7=O)=O)=O
InChi Code
InChI=1S/C71H122N6O33S/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-22-39(85)37(75-48(89)25-18-16-21-26-72-47(88)24-20-19-23-46-49-38(34-111-46)76-70(100)77-49)33-101-66-58(96)56(94)60(44(31-81)104-66)106-68-59(97)64(110-71(69(98)99)27-40(86)50(73-35(2)83)63(109-71)52(90)41(87)28-78)61(45(32-82)105-68)107-65-51(74-36(3)84)62(54(92)43(30-80)102-65)108-67-57(95)55(93)53(91)42(29-79)103-67/h17,22,37-46,49-68,78-82,85-87,90-97H,4-16,18-21,23-34H2,1-3H3,(H,72,88)(H,73,83)(H,74,84)(H,75,89)(H,98,99)(H2,76,77,100)/b22-17+/t37-,38-,39+,40-,41+,42+,43+,44+,45+,46-,49-,50+,51+,52+,53-,54-,55-,56+,57+,58+,59+,60+,61-,62+,63+,64+,65-,66+,67-,68-,71-/m0/s1
InChi Key
DPQSNMKTZRLKKS-FVAVKVGTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $769

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    Product Description

    C6 Biotin ganglioside GM1 is an affinity probe that allows ganglioside GM1 (Item No. 19579) to be detected or immobilized through interaction with the biotin ligand. C6 Biotin ganglioside GM1 has been used to detect ganglioside GM1 binding partners, such as CD206, in vitro.1 As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 2053]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chung, T.-W., Choi, H.-J., Park, M.-J., et al. The function of cancer-shed gangliosides in macrophage phenotype: Involvement with angiogenesis. Oncotarget 8(3), 4436-4448 (2017).