A fluorogenic substrate for HCMV protease
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Dabcyl-RGVVNASSRLA-EDANS (trifluoroacetate salt)

Item No. 24994

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N2-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-arginylglycyl-L-valyl-L-valyl-L-asparaginyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-leucyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-alaninamide, trifluoroacetate salt
Synonyms
  • Fluorogenic Human CMV Protease Substrate
Molecular Formula
C73H109N23O18S • XCF3COOH
Formula Weight
1628.9
Purity
≥95%
Formulation (Request formulation change)
A lyophilized powder
Solubility(Learn about Variance in Solubility)
Formic Acid: 1 mg/ml
SMILES
NC(NCCC[C@@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(NCCNC1=CC=CC2=C1C=CC=C2S(O)(=O)=O)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CO)=O)CO)=O)=O)CC(N)=O)=O)C(C)C)=O)C(C)C)=O)=O)NC(C3=CC=C(/N=N/C4=CC=C(N(C)C)C=C4)C=C3)=O)=N.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C73H109N23O18S.C2HF3O2/c1-38(2)33-52(66(106)84-41(7)61(101)80-32-31-79-49-17-11-16-48-47(49)15-12-20-56(48)115(112,113)114)88-65(105)51(19-14-30-82-73(77)78)87-68(108)55(37-98)91-69(109)54(36-97)90-62(102)42(8)85-67(107)53(34-57(74)99)89-70(110)60(40(5)6)93-71(111)59(39(3)4)92-58(100)35-83-64(104)50(18-13-29-81-72(75)76)86-63(103)43-21-23-44(24-22-43)94-95-45-25-27-46(28-26-45)96(9)10;3-2(4,5)1(6)7/h11-12,15-17,20-28,38-42,50-55,59-60,79,97-98H,13-14,18-19,29-37H2,1-10H3,(H2,74,99)(H,80,101)(H,83,104)(H,84,106)(H,85,107)(H,86,103)(H,87,108)(H,88,105)(H,89,110)(H,90,102)(H,91,109)(H,92,100)(H,93,111)(H4,75,76,81)(H4,77,78,82)(H,112,113,114);(H,6,7)/b95-94+;/t41-,42-,50-,51-,52-,53-,54-,55-,59-,60-;/m0./s1
InChi Key
QNMZTKAHIRYWTL-SOIWCTASSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $136

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    Product Description

    Dabcyl-RGVVNASSRLA-EDANS is a fluorogenic substrate for human cytomegalovirus (HCMV) protease.1 Upon enzymatic cleavage by HCMV protease at the Ala-Ser site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify HCMV protease activity. EDANS displays excitation/emission maxima of 340/485 nm, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Holskin, B.P., Bukhtiyarova, M., Dunn, B.M., et al. A continuous fluorescence-based assay of human cytomegalovirus protease using a peptide substrate. Anal. Biochem. 227(1), 148-155 (1995).