A fungal metabolite with diverse biological activities
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Penicolinate A

Item No. 25013

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,5'-(1,10-decanediyl)bis-2-pyridinecarboxylic acid, 2,2'-dimethyl ester
CAS Number
1418291-68-5
Synonyms
  • Penicolinate B dimethyl ester
Molecular Formula
C24H32N2O4
Formula Weight
412.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
O=C(OC)C1=NC=C(CCCCCCCCCC2=CN=C(C(OC)=O)C=C2)C=C1
InChi Code
InChI=1S/C23H30N2O4/c1-28-22(26)20-14-12-18(16-24-20)10-8-6-4-3-5-7-9-11-19-13-15-21(25-17-19)23(27)29-2/h12-17H,3-11H2,1-2H3
InChi Key
QZEIGUCIWCNWEF-UHFFFAOYSA-N
Origin
Fungus/Unidentified sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $307

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    5 mg

    $1,223

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    Product Description

    Penicolinate A is a fungal metabolite produced by Penicillium sp. BCC16054 with diverse biological activities.1 It exhibits antimalarial and antituberculosis activity (MICs = 3.25 and 12.5 mg/ml for P. falciparum and M. tuberculosis H37Ra, respectively). Penicolinate A is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s = 7.49, 18.43, 4.4, and 14.08 μM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Intaraudom, C., Boonyuen, N., Suvannakad, R., et al. Penicolinates A–E from endophytic Penicillium sp. BCC16054. Tetrahedron Lett. 54(8), 744-748 (2013).