A fungal metabolite
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Kumbicin C

Item No. 25015

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,8-di-1H-indol-3-yl-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-ol
CAS Number
1878151-58-6
Molecular Formula
C28H24N2O3
Formula Weight
436.5
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
CC1(C)C=CC2=C(C3=CNC4=C3C=CC=C4)C(O)=C(OC)C(C5=CNC6=C5C=CC=C6)=C2O1
InChi Code
InChI=1S/C28H24N2O3/c1-28(2)13-12-18-23(19-14-29-21-10-6-4-8-16(19)21)25(31)27(32-3)24(26(18)33-28)20-15-30-22-11-7-5-9-17(20)22/h4-15,29-31H,1-3H3
InChi Key
XQUDQEFLDBAHTH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    250 µg

    $219

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    1 mg

    $657

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    Cayman Chemical
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    Product Description

    Kumbicin C is a bis-indolyl benzenoid fungal metabolite produced by A. kumbius FRR6049.1 It inhibits the growth of NS-1 mouse myeloma cells (IC50 = 0.74 μg/ml). Kumbicin C also inhibits the growth of the Gram-positive bacteria B. subtilis (MIC = 1.6 μg/ml).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lacey, H.J., Vuong, D., Pitt, J.I., et al. Kumbicins A–D: Bis-Indolyl benzenoids and benzoquinones from an Australian soil fungus, Aspergillus kumbius. Aust. J. Chem. 69(2), 152-160 (2015).