A reduced form of galactose
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Isomer(s)
35597D-Iditol
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Galactitol

Item No. 25023

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
Galactitol
CAS Number
608-66-2
Synonyms
  • Dulcitol
  • NSC 1944
Molecular Formula
C6H14O6
Formula Weight
182.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): Slightly soluble
SMILES
OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO
InChi Code
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-
InChi Key
FBPFZTCFMRRESA-GUCUJZIJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

    $41

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    100 g

    $75

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    250 g

    $178

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    Product Description

    Galactitol is a reduced form of galactose (Item No. 20890) that has been found in various plants, including C. aculeatus.1 It is a toxic metabolite of galactose in humans that accumulates in the lens of patients with galactokinase deficiency-induced galactosemia, leading to cataract formation.2 Galactitol also accumulates in a transgenic mouse model of galactokinase deficiency, however, it does not lead to the formation of cataracts even with administration of a high-galactose diet.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tang, W.-H., Bai, S.-T., Tong, L., et al. Chemical constituents from Celastrus aculeatus Merr. Biochem. System. Ecol. 54, 78-82 (2014).

    2. Lai, K., Elsas, L.J., and Wierenga, K.J. Galactose toxicity in animals. IUBMB Life 61(11), 1063-1074 (2009).

    3. Ai, Y., Zheng, Z., O'Brein-Jenkins, A., et al. A mouse model of galactose-induced cataracts. Hum. Mol. Genet. 9(12), 1821-1827 (2000).