A fungal metabolite
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Aspochalasin M

Item No. 25087

Technical Information
Formal Name
(3S,3aR,4S,6aS,7E,12S,15aS)-3,3a,4,6a,9,10,13,14-octahydro-12-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,11,15(2H,12H)-trione
CAS Number
1173040-34-0
Molecular Formula
C24H35NO4
Formula Weight
Purity
≥95%
A solid
SMILES
C/C1=C\[C@]2([H])[C@@]3(C(CC[C@H](O)C(CC1)=O)=O)[C@@]([C@H](CC(C)C)NC3=O)([H])[C@H](C)C(C)=C2
InChi Code
InChI=1S/C24H35NO4/c1-13(2)10-18-22-16(5)15(4)12-17-11-14(3)6-7-19(26)20(27)8-9-21(28)24(17,22)23(29)25-18/h11-13,16-18,20,22,27H,6-10H2,1-5H3,(H,25,29)/b14-11+/t16-,17+,18+,20+,22+,24-/m1/s1
InChi Key
GBCXTRJHTIEBIA-CEXVAXOJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Aspochalasin M is a fungal metabolite originally isolated from S. elegans.1 It inhibits the growth of HL-60 cells (IC50 = 20 µM) but not MOLT-4, A549, or BEL-7402 cells (IC50s = >100 µg/ml).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lin, Z., Zhu, T., Wei, H., et al. Spicochalasin A and new aspochalasins from the marine-derived fungus Spicaria elegans. Eur. J. Org. Chem. 18, 3045-3051 (2009).