A polyphenol and flavonoid with diverse biological activities
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Enantiomer(s)
16944(−)-Gallocatechin
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(+)-Gallocatechin

Item No. 25125

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
CAS Number
970-73-0
Synonyms
  • NSC 674038
Molecular Formula
C15H14O7
Formula Weight
306.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 15 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
OC1=CC([C@@H]2[C@@H](O)CC3=C(O)C=C(O)C=C3O2)=CC(O)=C1O
InChi Code
InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15+/m0/s1
InChi Key
XMOCLSLCDHWDHP-SWLSCSKDSA-N
Origin
Plant/green tea
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $134

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    50 mg

    $213

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    100 mg

    $399

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    Cayman Chemical
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    Product Description

    (+)-Gallocatechin is a polyphenol and flavonoid that has been isolated from the leaves of tea plants and has diverse biological activities.1,2,3 It inhibits the adherence of P. gingivalis onto human buccal epithelial cells by more than 50% when used at a concentration of 250 μg/ml.4 (+)-Gallocatechin has antimutagenic properties in UV-irradiated E. coli cells.2 It inhibits cell death induced by D-galactosamine and TNF-α in primary cultured mouse hepatocytes by 29.9% when used at a concentration of 80 μM.3 (+)-Gallocatechin (100 μM) inhibits HCT116 colorectal cancer cell proliferation by 57%.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Du, G.J., Zhang, Z., Wen, X.D., et al. Epigallocatechin gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea. Nutrients 4(11), 1679-1691 (2012).

    2. Matsuo, T., Hanamure, N., Shimoi, K., et al. Identification of (+)-gallocatechin as a bio-antimutagenic compound in Psidium guava leaves. Phytochemistry 36(4), 1027-1029 (1994).

    3. Xiong, Q., Fan, W., Tezuka, Y., et al. Hepatoprotective effect of Apocynum venetum and its active constituents. Planta Med. 66(2), 127-133 (2000).

    4. Sakanaka, S., Aizawa, M., Kim, M., et al. Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. Biosci. Biotechnol. Biochem. 60(5), 745-749 (1996).