A mitochondrial dye
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MitoLite™ NIR FX690

Item No. 25163

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Emission
692 nm
Excitation
660 nm
Formulation (Request formulation change)
A solution in DMSO
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 tests

    $222

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    Product Description

    MitoLite™ reagents are fluorogenic probes that can be used to label mitochondria within live or fixed cells. They are hydrophobic and easily cross live cell membranes to accumulate in mitochondria likely via the mitochondrial membrane potential gradient. MitoLite™ reagents contain a cell-retaining group, which allows them to remain in the mitochondria long-term, and their fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. MitoLite™ NIR FX690 has been used to determine subcellular localization of photosensitizers modified by polyethylene glycol in HepG2 cells.1 MitoLite™ NIR FX690 displays excitation/emission maxima of 660/692 nm, respectively, and can be used for live and fixed cell applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zou, Q., Zhao, H., Zhao, Y., et al. Effective two-photon excited photodynamic therapy of xenograft tumors sensitized by water-soluble bis(arylidene)cycloalkanone photosensitizers. J. Med. Chem. 58(20), 7949-7958 (2015).